Genome-Wide Association Study of Body Conformation Traits in a Three-Way Crossbred Commercial Pig Population

Body conformation is the most direct production index, which can fully reflect pig growth status and closely related to critical economic traits. In this study, we conducted a genome-wide association study (GWAS) on body traits in population of 1518 Duroc × (Landrace Yorkshire) commercial pigs. These included length (BL), height (BH), chest circumference (CC), abdominal (AC), waist (WC). Both mixed linear model (MLM) fixed random circulating probability unification (FarmCPU) approaches were employed for analysis. Our findings revealed 60 significant single nucleotide polymorphisms (SNPs) associated with these crossbred population. Specifically, sixteen SNPs significantly BL, three BH, thirteen CC, twelve AC, WC. Moreover, identified several promising candidate genes located within genomic regions include INTS10, KIRREL3, SOX21, BMP2, MAP4K3, SOD3, FAM160B1, ATL2, SPRED2, SEC16B, RASAL2. Furthermore, our analysis novel quantitative trait locus (QTL) SSC7 specifically circumference, spanning an 84 kb interval. Overall, identification potential pigs enhances understanding genetic basis underlying Additionally, provide valuable resources breeding programs.